Description

Pleconaril CAS NO 153168-05-9 is a synthetic antiviral compound belonging to the class of capsid inhibitors. It is primarily valued for its targeted mechanism of action against picornaviruses, which are responsible for a range of human illnesses. This compound is of significant interest to pharmaceutical research and development organizations focused on antiviral therapeutics, particularly for conditions like the common cold and viral meningitis.

Application

• Antiviral Drug Research & Development: As a lead compound or reference standard in the discovery and development of novel antiviral medications targeting enteroviruses and rhinoviruses.
• Pharmacological Studies: Used in in vitro and in vivo studies to investigate viral replication mechanisms, host-pathogen interactions, and drug resistance profiles.
• Reference Standard for QC/QA: Serves as a high-purity analytical standard in quality control laboratories for method development, validation, and assay calibration in pharmaceutical manufacturing.
• Biochemical Research: Employed in biochemical assays to study viral capsid assembly and function, aiding in fundamental virology research.
• Clinical Trial Materials: Supplied as a key active pharmaceutical ingredient (API) intermediate or finished dosage form component for preclinical and clinical trial stages.

Basic Information

Product Name	Pleconaril
CAS No.	153168-05-9
Molecular Formula	C₂₇H₂₀F₃N₃O₄
Molecular Weight	507.46 g/mol
Synonyms	3-{3,5-Dimethyl-4-[[3-(3-methyl-5-isoxazolyl)propyl]oxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole; VP 63843; Picovir; (RS)-Pleconaril; 1,2,4-Oxadiazole, 3-[3,5-dimethyl-4-[[3-(3-methyl-5-isoxazolyl)propyl]oxy]phenyl]-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our Pleconaril is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent standards suitable for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.