Description

Inolimomab is a monoclonal antibody designed to target the interleukin-2 receptor alpha chain (CD25). This compound is a critical research tool and therapeutic candidate for modulating immune responses. It is primarily utilized in advanced pharmaceutical research and development for investigating and treating conditions related to T-cell activation, such as graft-versus-host disease (GvHD) and certain autoimmune disorders. Our supply ensures high purity and batch-to-batch consistency for reliable experimental and developmental outcomes.

Application

• Immunological Research: A key reagent for studying T-cell activation, proliferation, and the IL-2 signaling pathway in vitro and in vivo.
• Therapeutic Development: Investigational agent for the treatment and prevention of acute graft-versus-host disease (GvHD) following hematopoietic stem cell transplantation.
• Autoimmune Disease Models: Used in preclinical research to investigate potential therapies for autoimmune conditions by targeting activated T-cells.
• Biomarker Studies: Employed in flow cytometry and immunohistochemistry to identify and quantify CD25-expressing cell populations.
• Process Development: Serves as a reference standard in the development and quality control of biopharmaceutical manufacturing processes for monoclonal antibodies.

Basic Information

Product Name	Inolimomab
CAS No.	152981-31-2
Molecular Formula	C6450H9916N1696O2016S46
Molecular Weight	~145 kDa
Synonyms	Anti-IL-2 Receptor alpha antibody; Anti-CD25 antibody; Anti-Tac antibody; B-B10; LO-CD25a; Inolimomab (INN); Anti-IL-2Rα; Anti-p55; Anti-IL2RA; Murine monoclonal antibody to CD25
EINECS	Contact for details

Quality Control

Our Inolimomab is produced and tested under stringent conditions to ensure it meets the high standards required for research and development. Each batch is characterized for identity, purity, potency, and stability. Comprehensive analysis includes SDS-PAGE, size-exclusion HPLC, and binding affinity assays. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Consistent with monoclonal antibody profile
Purity (SEC-HPLC)	≥ 95% (Monomer)
Protein Content (UV)	≥ 1.0 mg/vial
Endotoxin (LAL)	< 1.0 EU/mg
Binding Activity (ELISA/Flow Cytometry)	Conforms to reference standard
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.