Description

Dacliximab CAS NO 152923-56-3 is a chimeric monoclonal antibody specifically designed to target the interleukin-2 receptor alpha chain (CD25). This product is a critical biopharmaceutical agent used for targeted immunosuppression. It is primarily utilized in the prevention of acute organ transplant rejection, offering a targeted mechanism to modulate the immune response. Its high specificity makes it an essential component in advanced therapeutic regimens within hospital and clinical research settings.

Application

• Prophylaxis of Acute Organ Rejection: Used in combination with other immunosuppressants to prevent kidney transplant rejection.
• Immunosuppressive Therapy: Management of T-cell mediated immune responses in transplant patients.
• Clinical Research: Serves as a reference standard or active pharmaceutical ingredient (API) in immunological studies and drug development.
• Biopharmaceutical Manufacturing: Key intermediate in the production of finished dosage forms for immunosuppressive treatments.
• Hospital & Clinical Use: Administered as part of induction therapy prior to transplantation.

Basic Information

Product Name	Dacliximab
CAS No.	152923-56-3
Molecular Formula	C6370H9868N1692O1997S46
Molecular Weight	Approx. 144 kDa
Synonyms	Daclizumab; Anti-Tac; Anti-IL-2Rα; Anti-CD25 Antibody; Zenapax; Chimeric Anti-Tac; Dacliximab (USAN); RO24-7375; Anti-Interleukin-2 Receptor Subunit Alpha Antibody
EINECS	Contact for details

Quality Control

Our Dacliximab is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, meeting stringent standards for biopharmaceutical actives. Certificates of Analysis (COA) detailing specifications such as purity by HPLC, biological activity, endotoxin levels, and sterility are provided to guarantee compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at 2-8°C. Reconstituted solutions should be used immediately or stored as directed. Due to its hygroscopic nature, protect from moisture. Store in a dedicated, controlled environment.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 98.0% (Monomer)
Protein Content	≥ 95.0% (by UV)
Biological Activity (Bioassay)	Conforms to reference
Endotoxin	< 1.0 EU/mg
Residual Moisture (KF)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.