Description

Glycerol-1,2,3-3H is a high-specific-activity tritium-labeled form of glycerol, a fundamental biochemical building block. This labeled compound is essential for precise metabolic and pharmacokinetic tracer studies, enabling researchers to track biochemical pathways with high sensitivity. It is a critical reagent for life science research, pharmaceutical development, and analytical chemistry applications requiring radiolabeled tracers.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study lipid biosynthesis, gluconeogenesis, and energy metabolism in biological systems.
• Drug Metabolism & Pharmacokinetics (DMPK): Employed in ADME (Absorption, Distribution, Metabolism, Excretion) studies to track the fate of drug candidates or prodrugs metabolized through glycerol pathways.
• Biochemical Research: Serves as a precursor in the synthesis of radiolabeled phospholipids, triglycerides, and other complex lipids for membrane and signaling studies.
• Diagnostic Agent Development: Acts as a starting material for developing novel radiolabeled diagnostic probes and imaging agents.
• Environmental & Agricultural Science: Applied in tracing organic compound degradation and studying microbial metabolism in environmental samples.

Basic Information

Product Name	Glycerol-1,2,3-3H
CAS No.	152558-61-7
Molecular Formula	C3H53H3O3
Molecular Weight	95.10 g/mol (for 3H3 form)
Synonyms	Glycerol (tritiated); [1,2,3-3H]Glycerol; Glycerin-3H; 1,2,3-Tritioglycerol; Tritium-labeled Glycerol; Propane-1,2,3-triol-1,2,3-3H; Glycerol tri-tritiate
EINECS	Contact for details

Quality Control

Every batch of Glycerol-1,2,3-3H is manufactured and analyzed under strict quality systems. We ensure high radiochemical purity and specific activity through advanced analytical techniques including HPLC with radiometric detection. Certificates of Analysis (COA) detailing specific activity, purity, solvent composition, and analytical methods are provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated area for radioactive materials. Follow all local, national, and international regulations for the safe handling and storage of radiolabeled compounds.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR / NMR)	Conforms to structure
Specific Activity	10-50 Ci/mmol (Typical range, custom available)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC / GC)	≥ 98%
Solvent	Ethanol:Water (9:1) or as specified
Concentration	1 mCi/mL (Typical, custom available)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.