Description

4-Fluoro-3-Methylcinnamic Acid is a high-purity fluorinated cinnamic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and methyl substituents, makes it a valuable intermediate for modulating the physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced potency and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting inflammation, oncology, and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic semiconductors and liquid crystal compounds for electronic displays.
• Polymer Modification: Employed to introduce fluorinated aromatic groups into polymer backbones to enhance thermal stability, chemical resistance, and optical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fluorescent Probe & Dye Synthesis: Used as a building block for creating specialized fluorophores and molecular probes for bioimaging and diagnostic applications.

Basic Information

Product Name	4-Fluoro-3-Methylcinnamic Acid
CAS No.	152152-18-6
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	(E)-3-(4-Fluoro-3-methylphenyl)acrylic acid; 3-(4-Fluoro-3-methylphenyl)-2-propenoic acid; 4-Fluoro-3-methyl-trans-cinnamic acid; trans-4-Fluoro-3-methylcinnamic acid; 2-Propenoic acid, 3-(4-fluoro-3-methylphenyl)-, (2E)-; 4-Fluoro-m-methylcinnamic acid; 3-Methyl-4-fluorocinnamic acid; FMMCA
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methylcinnamic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices. Custom purity grades, including pharmaceutical intermediates grade, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.