Description

2,6-Difluorocinnamic Acid is a high-value fluorinated aromatic building block characterized by its cinnamic acid core with fluorine substituents at the 2 and 6 positions. This specific substitution pattern is critical for modulating the electronic and steric properties of downstream molecules, making it a sought-after intermediate in advanced synthetic chemistry. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators where the difluoro motif enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated organic electronic materials, contributing to improved charge transport and thermal stability in display and lighting technologies.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, weatherability, and specific optical properties.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the exploration of new fluorination reactions and coupling chemistries.

Basic Information

Product Name	2,6-Difluorocinnamic Acid
CAS No.	152152-09-5
Molecular Formula	C9H6F2O2
Molecular Weight	184.14 g/mol
Synonyms	(2,6-Difluorophenyl)acrylic acid; 3-(2,6-Difluorophenyl)-2-propenoic acid; 2,6-Difluoro-trans-cinnamic acid; trans-2,6-Difluorocinnamic acid; 2,6-DFCA; 2,6-Difluorobenzeneacrylic acid; (E)-3-(2,6-Difluorophenyl)acrylic acid
EINECS	Contact for details

Quality Control

Our 2,6-Difluorocinnamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.