Description

Benzoyl Fluoride, 2-Chloro-4-Fluoro- (9Ci) is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic introduction of both fluorine and chlorine substituents onto a benzoyl fluoride scaffold, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for enhanced bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms can improve compound efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Acts as a building block for fluorinated aromatic cores in advanced electronic and display materials.
• Cross-Coupling Reactions: The benzoyl fluoride group can participate in various transition metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Fluorination Reagent Precursor: Can be utilized to generate other fluorinating agents or to introduce the benzoyl group into target molecules under mild conditions.
• Polymer Chemistry: Employed in the synthesis of specialty polymers, where halogenated monomers impart specific properties like chemical resistance or thermal stability.

Basic Information

Product Name	Benzoyl Fluoride, 2-Chloro-4-Fluoro- (9Ci)
CAS No.	152125-93-4
Molecular Formula	C7H3ClF2O
Molecular Weight	176.55 g/mol
Synonyms	2-Chloro-4-fluorobenzoyl fluoride; 2-Chloro-4-fluorobenzoic acid fluoride; 2-Chloro-α,α,α,4-tetrafluorotoluene (incorrect but sometimes listed); Benzoic acid, 2-chloro-4-fluoro-, fluoride; (2-Chloro-4-fluorophenyl)(fluoro)methanone
EINECS	Contact for details

Quality Control

Our Benzoyl Fluoride, 2-Chloro-4-Fluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.