Description

(S)-4-(2-Hydroxyethyl)-2,2-Diisopropyl-1,3-Dioxolane is a high-purity chiral building block and protecting group reagent. This compound is valued for its role in the stereoselective synthesis of complex organic molecules, particularly in pharmaceutical development. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating active ingredients and advanced intermediates.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key building block for the production of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis & Ligand Synthesis: Used in the preparation of chiral ligands and catalysts for stereoselective reactions.
• Agrochemical Research: Employed in the development of novel, enantioselective pesticides and herbicides.
• Fine Chemical Manufacturing: Serves as a precursor for specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic and medicinal chemistry.
• Protecting Group Chemistry: The dioxolane moiety can act as a protecting group for diols or carbonyl functionalities in multi-step syntheses.

Basic Information

Product Name	(S)-4-(2-Hydroxyethyl)-2,2-Diisopropyl-1,3-Dioxolane
CAS No.	151223-12-0
Molecular Formula	C11H22O3
Molecular Weight	202.29 g/mol
Synonyms	(S)-2,2-Diisopropyl-4-(2-hydroxyethyl)-1,3-dioxolane; (S)-4-(2-Hydroxyethyl)-2,2-bis(1-methylethyl)-1,3-dioxolane; (S)-1,2-O-Isopropylidene-1,2,4-butanetriol cyclic isopropylidene acetal; (S)-DIPT-diol acetonide; (S)-DIPT Glycol; Chiral Dioxolane Derivative
EINECS	Contact for details

Quality Control

Our (S)-4-(2-Hydroxyethyl)-2,2-Diisopropyl-1,3-Dioxolane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage or after opening to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.