Description

1-(2-Fluorophenyl)Cyclobutanecarboxylic Acid is a high-value fluorinated cyclobutane derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its unique structure, combining a fluorinated aromatic ring with a strained cyclobutane carboxylic acid, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom and rigid cyclobutane ring can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands and catalysts for asymmetric synthesis.
• Material Science: Serves as a monomer or building block for advanced polymers and liquid crystals, where its structural rigidity can impart desired thermal and optical properties.
• Chemical Biology Probe Synthesis: Utilized to create fluorinated probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	1-(2-Fluorophenyl)Cyclobutanecarboxylic Acid
CAS No.	151157-48-1
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	2-Fluorophenylcyclobutanecarboxylic Acid; 1-(2-Fluorophenyl)cyclobutane-1-carboxylic acid; Cyclobutanecarboxylic acid, 1-(2-fluorophenyl)-; 1-(o-Fluorophenyl)cyclobutanecarboxylic Acid; 2-Fluorobenzenecyclobutanecarboxylic Acid; 1-(2-Fluorophenyl)-1-cyclobutanecarboxylic Acid; (2-Fluorophenyl)cyclobutanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorophenyl)Cyclobutanecarboxylic Acid is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment ensures batch-to-batch consistency and traceability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.