Description

Indinavir is a potent and selective protease inhibitor used as an active pharmaceutical ingredient (API) in antiretroviral therapy. Its primary value lies in its critical role in combination therapies for the treatment of Human Immunodeficiency Virus (HIV) infection. This high-purity compound is essential for pharmaceutical manufacturers and research institutions developing and producing life-saving antiviral medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of antiretroviral drugs for HIV treatment.
• Fixed-Dose Combination Drugs: Used in the development and production of combination therapies with other antiretroviral agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Clinical Research: Utilized in preclinical and clinical studies for the development of new HIV treatment regimens and formulations.
• Generic Drug Manufacturing: A key component for companies producing generic versions of antiretroviral medications.

Basic Information

Item	Detail
Product Name	Indinavir
CAS No.	150378-17-9
Molecular Formula	C36H47N5O4
Molecular Weight	613.80 g/mol
Synonyms	Indinavir Sulfate; L-735,524; MK-639; Crixivan® (brand name); (2S)-1-[(2S,4R)-4-Benzyl-2-hydroxy-4-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl]butyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide; [1(1S,2R),5(S)]-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-[2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide
EINECS	Contact for details

Quality Control

Our Indinavir is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC. A Certificate of Analysis (COA) documenting compliance with relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.