Description

(R)-2-Diphenyphosphino-2'-Hydroxyl-1,1'-Binaphthyl CAS NO 149917-88-4 is a high-value, chiral monophosphine ligand widely used in asymmetric synthesis. Its primary value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for producing single-enantiomer pharmaceutical intermediates and fine chemicals. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity chiral auxiliaries.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical active ingredients.
• Catalyst component for asymmetric C-C bond-forming reactions, such as cross-coupling and allylic substitution.
• Key reagent in the synthesis of enantiomerically pure agrochemicals and flavors/fragrances.
• Used in academic and industrial research for developing new catalytic asymmetric methodologies.
• Component in catalyst systems for the production of chiral alcohols, amines, and other functionalized molecules.
• Potential application in materials science for creating chiral polymers or surfaces.

Basic Information

Product Name	(R)-2-Diphenyphosphino-2'-Hydroxyl-1,1'-Binaphthyl
CAS No.	149917-88-4
Molecular Formula	C32H23O1P1
Molecular Weight	454.50 g/mol
Synonyms	(R)-2-Diphenylphosphino-2'-hydroxy-1,1'-binaphthyl; (R)-2-(Diphenylphosphino)-2'-hydroxy-1,1'-binaphthyl; (R)-HOBINAP; (R)-2-(Diphenylphosphino)-2'-hydroxy-1,1'-binaphthyl; (R)-2-Diphenylphosphino-2'-hydroxy-1,1'-binaphthyl; (R)-2-Diphenylphosphanyl-2'-hydroxy-1,1'-binaphthalene; (R)-HOBINAP Ligand
EINECS	Contact for details

Quality Control

Our (R)-2-Diphenyphosphino-2'-Hydroxyl-1,1'-Binaphthyl is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, typically ≥98% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP standards where applicable, ensuring the material is suitable for demanding applications in pharmaceutical development and other regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.