Description

2-Amino-6-Chloro-9-(2-(Hydroxymethyl)-1,3-Oxathiolan-5-Yl)Purine CAS NO 149819-73-8 is a high-purity nucleoside analog intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters as a critical building block for the development of antiviral and anticancer therapeutics, where precise molecular structure is paramount. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for nucleoside-based drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analog antiviral agents.
• Antiviral Drug Research: Used in the research and development of potential treatments targeting viral polymerases.
• Oncology Research: Serves as a building block for experimental anticancer compounds that interfere with DNA/RNA synthesis.
• Biochemical Research: Employed in studies of enzyme kinetics and mechanisms involving purine analogs.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	2-Amino-6-Chloro-9-(2-(Hydroxymethyl)-1,3-Oxathiolan-5-Yl)Purine
CAS No.	149819-73-8
Molecular Formula	C9H10ClN5O2S
Molecular Weight	287.73 g/mol
Synonyms	6-Chloro-2-amino-9-[(2-hydroxymethyl)-1,3-oxathiolan-5-yl]purine; 2-Amino-6-chloro-9-[(2-hydroxymethyl)-1,3-oxathiolan-5-yl]-9H-purine; 2-Amino-6-chloro-9-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)purine; Lamivudine Impurity; Lamivudine Related Compound; Oxathiolanyl Purine Derivative; Nucleoside Analog Intermediate
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Chloro-9-(2-(Hydroxymethyl)-1,3-Oxathiolan-5-Yl)Purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.