Description

2,4,5-Trifluoro-3-Methoxy-6-Nitrobenzoic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique trifluoro-methoxy-nitro substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Advanced Polymer Chemistry: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and other transformations to introduce a multi-functionalized benzoic acid moiety.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	2,4,5-Trifluoro-3-Methoxy-6-Nitrobenzoic Acid
CAS No.	149707-41-5
Molecular Formula	C8H4F3NO5
Molecular Weight	251.12 g/mol
Synonyms	2,4,5-Trifluoro-3-methoxy-6-nitrobenzoic acid; 3-Methoxy-2,4,5-trifluoro-6-nitrobenzoic acid; 6-Nitro-2,4,5-trifluoro-3-methoxybenzoic acid; Benzoic acid, 2,4,5-trifluoro-3-methoxy-6-nitro-; 149707-41-5; 2,4,5-Trifluoro-3-methoxy-6-nitro-benzoic acid; 2,4,5-Trifluoro-3-methoxy-6-nitrobenzoic acid (CAS 149707-41-5)
EINECS	Contact for details

Quality Control

Our production of 2,4,5-Trifluoro-3-Methoxy-6-Nitrobenzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure consistency and reliability. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.