Description

Trovirdine CAS NO 149488-17-5 is a synthetic, non-nucleoside reverse transcriptase inhibitor (NNRTI) with potent antiviral activity. This compound is of significant interest for its targeted mechanism of action against specific viral strains, making it a valuable research chemical. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in antiviral drug discovery and development programs.

Application

• Antiviral Research & Development: A key intermediate or reference standard in the synthesis and study of novel non-nucleoside reverse transcriptase inhibitors (NNRTIs).
• Biochemical Assay Development: Used as a pharmacological tool to study enzyme kinetics, inhibition mechanisms, and resistance profiles in virology research.
• Pharmaceutical Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method validation in drug manufacturing.
• Mechanistic Studies: Employed in cellular and molecular biology research to investigate viral replication cycles and host-pathogen interactions.
• Preclinical Development: Utilized in *in vitro* and *in vivo* studies to evaluate the efficacy, pharmacokinetics, and toxicology of antiviral candidate compounds.

Basic Information

Product Name	Trovirdine
CAS No.	149488-17-5
Molecular Formula	C22H21N5O3S
Molecular Weight	435.50 g/mol
Synonyms	Trovirdine; LY 300046; 6-(3,5-Dimethylbenzyl)-1-[(1-methylethyl)sulfonyl]-1,5-dihydro-4H-imidazo[4,5,1-ij]quinolin-2,4-dione; 6-[(3,5-Dimethylphenyl)methyl]-1-(propan-2-ylsulfonyl)-1,5-dihydro-4H-imidazo[4,5,1-ij]quinoline-2,4-dione; LY-300046; 1-Isopropylsulfonyl-6-(3,5-dimethylbenzyl)imidazo[4,5,1-ij]quinoline-2,4(1H,5H)-dione
EINECS	Contact for details

Quality Control

Our Trovirdine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.