Description

Methyl 2-(Trifluoromethoxy)Benzoate is a high-value fluorinated aromatic ester building block. This compound is essential for introducing the unique trifluoromethoxy (OCF₃) pharmacophore into advanced molecular structures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its properties can enhance metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, or specific optical properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to construct complex, fluorinated aromatic systems for various R&D applications.

Basic Information

Product Name	Methyl 2-(Trifluoromethoxy)Benzoate
CAS No.	148437-99-4
Molecular Formula	C₉H₇F₃O₃
Molecular Weight	220.15 g/mol
Synonyms	Methyl o-(Trifluoromethoxy)benzoate; 2-(Trifluoromethoxy)benzoic acid methyl ester; Benzoic acid, 2-(trifluoromethoxy)-, methyl ester; Methyl 2-(trifluoromethoxy)benzoate; Methyl 2-(trifluoromethoxy)benzoate (CAS 148437-99-4); o-(Trifluoromethoxy)benzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-(Trifluoromethoxy)Benzoate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identity confirmation, and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.