Description

Orotic Acid-15N2 is a stable isotope-labeled analog of orotic acid, a key intermediate in pyrimidine biosynthesis. This high-purity labeled compound is essential for advanced research and analytical applications requiring precise metabolic tracing and quantification. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, nutritional science, and stable isotope labeling for mass spectrometry.

Application

• Stable Isotope Labeling for Mass Spectrometry (MS): Serves as an internal standard for the accurate quantification of orotic acid and related metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Used in in vitro and in vivo studies to elucidate the biosynthesis and turnover of pyrimidine nucleotides.
• Pharmaceutical Research & Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug candidates and their metabolites.
• Nutritional and Clinical Research: Facilitates studies on nucleotide metabolism, urea cycle disorders, and conditions related to orotic aciduria.
• Biochemical Reagent Manufacturing: A critical raw material for producing high-value diagnostic kits and specialized biochemical reagents.

Basic Information

Product Name	Orotic Acid-15N2
CAS No.	147687-63-6
Molecular Formula	C5H415N2O4
Molecular Weight	158.10 g/mol (for 15N2)
Synonyms	6-Carboxyuracil-15N2; Vitamin B13-15N2; 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid-15N2; Wheeler-LaFond acid-15N2; Animal galactose factor-15N2; [15N2]-Orotic Acid
EINECS	Contact for details

Quality Control

Our Orotic Acid-15N2 is manufactured under strict quality control protocols to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical results from techniques such as NMR and HPLC-MS. We adhere to cGMP principles for consistent quality and supply reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (15N)	≥ 98 atom %
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.