Description

Telenzepine Dihydrochloride is a high-purity, muscarinic receptor antagonist compound of significant interest in pharmaceutical research and development. Its primary value lies in its potent and selective pharmacological activity, which makes it a critical reference standard and active pharmaceutical ingredient (API) intermediate. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on developing treatments for gastrointestinal disorders and studying cholinergic systems.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in API manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis of advanced drug candidates targeting muscarinic receptors.
• Biomedical Research: Employed in in vitro and in vivo studies to investigate the role of muscarinic receptors in physiological and pathological processes.
• Drug Discovery & Development: A crucial tool for high-throughput screening (HTS) and pharmacological profiling in preclinical research stages.
• Academic Research: Utilized in university and institutional labs for fundamental studies in neuropharmacology and gastroenterology.
• Contract Research Organization (CRO) Services: Supplied to CROs conducting client-sponsored drug development and toxicology studies.

Basic Information

Product Name	Telenzepine Dihydrochloride
CAS No.	147416-96-4
Molecular Formula	C19H23N3O3·2HCl
Molecular Weight	414.32 g/mol (Free base: 341.41 g/mol)
Synonyms	Telenzepine HCl; Telenzepine dihydrochloride; 3,11-Dihydro-9-acridinyloxy-5-methyl-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride; AF-DX 116; (11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride); AQ-RA 741; Muscarinic M2 receptor antagonist telenzepine
EINECS	Contact for details

Quality Control

Our Telenzepine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.