Description

Loviride is a high-purity pharmaceutical intermediate and active ingredient with significant importance in antiviral research and development. Its primary value lies in its role as a key building block for synthesizing novel nucleoside analogs, which are crucial for creating effective antiviral therapies. This compound is essential for pharmaceutical manufacturers, research institutions, and CROs/CMOs engaged in the development of treatments for viral infections.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of advanced nucleoside-based antiviral agents.
• Antiviral Drug Research: Serves as a key scaffold for the discovery and development of new therapeutic compounds targeting specific viral enzymes.
• Biochemical Research: Used in enzymatic studies and as a reference standard to understand mechanisms of viral inhibition.
• Process Development: Employed in scaling up and optimizing synthetic routes for the commercial production of active pharmaceutical ingredients (APIs).
• Contract Manufacturing: Supplied to CMOs for the production of custom antiviral compounds under cGMP conditions.

Basic Information

Product Name	Loviride
CAS No.	147362-57-0
Molecular Formula	C8H11N5O3S
Molecular Weight	257.27 g/mol
Synonyms	2',3'-Dideoxy-3'-thiacytidine; 3TC; Lamivudine intermediate; (-)-2',3'-Dideoxy-3'-thiacytidine; BCH-189; GR-109714X; Epivir intermediate; cis-1-(2-Hydroxymethyl-1,3-oxathiolan-5-yl)cytosine
EINECS	Contact for details

Quality Control

Our Loviride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, chiral purity, and residual solvent analysis, to meet the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) are available for every batch and can be tailored to include specific tests as required for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.