Description

Delavirdine, Mesylate CAS NO 147221-93-0 is the mesylate salt form of Delavirdine, a potent and selective non-nucleoside reverse transcriptase inhibitor (NNRTI). This high-purity pharmaceutical intermediate is critical for ensuring the efficacy and safety of finished drug products. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antiretroviral therapies.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key intermediate in the commercial-scale manufacturing of Delavirdine-based antiretroviral medications.
• Pharmaceutical Research & Development: Used in preclinical and clinical studies for investigating new formulations or combination therapies targeting HIV-1.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development, validation, and routine testing of drug substances and products.
• Process Chemistry: Utilized in optimizing synthetic routes and scaling up production processes for NNRTI-class drugs.

Basic Information

Product Name	Delavirdine, Mesylate
CAS No.	147221-93-0
Molecular Formula	C22H28N6O3S • CH4O3S
Molecular Weight	552.65 g/mol
Synonyms	Delavirdine Mesylate; Delavirdine Methanesulfonate; U-90152S; BHAP U-90152; Rescriptor Mesylate (trade name related); 1-[3-[(1-Methylethyl)amino]-2-pyridinyl]-4-[[5-[(methylsulfonyl)amino]-1H-indol-2-yl]carbonyl]piperazine monomethanesulfonate; NSC 648903
EINECS	Contact for details

Quality Control

Our Delavirdine, Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.