Description

Carbamic Acid, [(1S)-1-Phenylethyl]-, 1,1-Dimethylethyl Ester is a chiral carbamate derivative of significant interest in advanced organic synthesis. This compound serves as a crucial protected intermediate for the construction of complex molecules, particularly in pharmaceutical development. It is primarily utilized by research institutions and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of enantiomerically pure drugs, particularly those targeting the central nervous system.
• Asymmetric Synthesis: Used as a chiral auxiliary or a protected amine precursor in stereoselective chemical reactions.
• Peptidomimetics Research: Employed in the development of peptide-like compounds with enhanced metabolic stability for therapeutic applications.
• Agrochemical Synthesis: Serves as an intermediate in the production of certain chiral pesticides and herbicides.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry laboratories and for exploring new synthetic pathways.

Basic Information

Product Name	Carbamic Acid, [(1S)-1-Phenylethyl]-, 1,1-Dimethylethyl Ester
CAS No.	147169-48-0
Molecular Formula	C13H19NO2
Molecular Weight	221.30 g/mol
Synonyms	(S)-tert-Butyl (1-phenylethyl)carbamate; (S)-N-(1-Phenylethyl)carbamic Acid tert-Butyl Ester; (S)-1-Phenylethylcarbamic Acid tert-Butyl Ester; (S)-Boc-1-Phenylethylamine; (S)-N-Boc-α-Methylbenzylamine; (S)-tert-Butyl (α-Methylbenzyl)carbamate; (S)-N-(α-Methylbenzyl)carbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. All materials are characterized using advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess, and impurity profile is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.