Description

Tenofovir is a potent nucleotide reverse transcriptase inhibitor (NRTI) with significant antiviral activity. This high-purity active pharmaceutical ingredient (API) is critical for the formulation of antiviral medications targeting chronic infections. It is essential for pharmaceutical manufacturers and research institutions developing treatments for hepatitis B virus (HBV) and human immunodeficiency virus (HIV).

Application

• Primary Active Pharmaceutical Ingredient (API) in antiviral drug formulations.
• Key component in the synthesis of Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) prodrugs.
• Research and development of novel antiviral therapies and combination drugs.
• Manufacturing of generic antiviral medications for global healthcare programs.
• Reference standard for quality control and analytical testing in pharmaceutical laboratories.
• Intermediate in advanced pharmaceutical research exploring nucleotide analogs.

Basic Information

Product Name	Tenofovir
CAS No.	147127-20-6
Molecular Formula	C9H14N5O4P
Molecular Weight	287.21 g/mol
Synonyms	(R)-9-(2-Phosphonomethoxypropyl)adenine; PMPA; GS-1278; (R)-PMPA; (R)-9-[2-(Phosphonomethoxy)propyl]adenine; 9-[(R)-2-(Phosphonomethoxy)propyl]adenine; Tenofovir (USAN); Viread (brand name reference)
EINECS	Contact for details

Quality Control

Our Tenofovir is manufactured under strict quality management systems. We provide material that meets or exceeds relevant pharmacopeial standards, including USP and EP monographs where applicable. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles to ensure compliance with your stringent requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.