Description

Isooxodesmosine CAS NO 147044-50-6 is a specialized biochemical compound, a derivative of the advanced glycation end-product (AGE) family, known for its role in protein cross-linking. This compound is of significant interest in biochemical and medical research for studying connective tissue aging, fibrosis, and the molecular mechanisms of diabetes-related complications. It serves as a critical analytical standard and research reagent for scientists and laboratories in the fields of pharmaceutical R&D, clinical diagnostics, and advanced material science.

Application

• Biochemical Research Standard: Used as a high-purity reference standard for the quantification and study of advanced glycation end-products (AGEs) in biological samples.
• Connective Tissue Studies: Essential for investigating collagen and elastin cross-linking, providing insights into skin aging, arterial stiffness, and pulmonary fibrosis.
• Diabetic Complication Research: A key analyte in research focused on the pathophysiology of long-term diabetic complications, such as nephropathy and retinopathy.
• Diagnostic Assay Development: Employed in the development and calibration of immunoassays (ELISA) and chromatographic methods (LC-MS/MS) for AGE detection.
• Pharmaceutical Screening: Used in drug discovery programs aimed at identifying anti-glycation or AGE-breaker compounds for therapeutic applications.
• Nutritional & Cosmetic Science: Applied in studies evaluating the anti-aging effects of nutraceuticals and topical agents by measuring their impact on AGE formation.

Basic Information

Product Name	Isooxodesmosine
CAS No.	147044-50-6
Molecular Formula	C20H30N4O8
Molecular Weight	454.48 g/mol
Synonyms	Iso-oxodesmosine; Oxodesmosine Isomer; AGE Isooxodesmosine; (2S)-2-Amino-5-[(4S)-4-amino-4-carboxybutyl]-1-(5S)-5-amino-5-carboxypentyl)-3,5-dihydro-4H-imidazol-4-one; Desmosine Analog; Pyridinium Cross-link Analog; Elastin Cross-linkage Marker
EINECS	Contact for details

Quality Control

Our Isooxodesmosine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive analytical applications. Each lot is characterized using advanced techniques including HPLC, mass spectrometry, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.