Description

Talsaclidine Fumarate CAS NO 147025-54-5 is a high-purity, non-racemic salt form of a selective muscarinic M1 receptor agonist. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential in studying cholinergic pathways and cognitive function. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, neuropharmacology, and the development of treatments for neurological disorders.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for analytical method development, validation, and quality control in drug substance and product testing.
• Neuroscience Research: Used as a selective pharmacological tool to investigate the role of muscarinic M1 receptors in synaptic plasticity, learning, and memory processes.
• Drug Discovery & Development: Employed in preclinical studies for the development of novel therapeutics targeting Alzheimer's disease, schizophrenia, and other cognitive impairments.
• Biochemical Assays: Acts as a key reagent in receptor binding studies, functional cellular assays, and high-throughput screening (HTS) campaigns.
• Academic Research: Utilized in university and institutional labs for fundamental research into cholinergic system biology and receptor pharmacology.

Basic Information

Product Name	Talsaclidine Fumarate
CAS No.	147025-54-5
Molecular Formula	C14H21N3O2 • C4H4O4
Molecular Weight	407.43 g/mol
Synonyms	(+)-WAL 2014 FU; (R)-3-(Prop-2-ynylamino)quinuclidine fumarate; (R)-N-(Prop-2-yn-1-yl)quinuclidin-3-amine fumarate; Talsaclidine; Talsaclidine (WAL 2014) fumarate; WAL 2014 FU; WAL-2014-FU; (3R)-3-[(2-Propyn-1-yl)amino]quinuclidine (E)-2-butenedioate (1:1)
EINECS	Contact for details

Quality Control

Our Talsaclidine Fumarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and other relevant pharmacopeial methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0% (anhydrous basis)
Chiral Purity (Chiral HPLC)	≥99.0% (R-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.