Description

Talsaclidine CAS NO 147025-53-4 is a selective muscarinic acetylcholine receptor agonist, specifically targeting the M1 receptor subtype. This compound is a valuable research chemical and pharmaceutical intermediate for the development of treatments targeting cognitive disorders and neurodegenerative diseases. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) for preclinical and clinical studies.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis of novel muscarinic receptor-targeting therapeutics.
• Neuropharmacology Studies: Used as a selective M1 receptor agonist in vitro and in vivo to study cholinergic system function and receptor mechanisms.
• Cognitive Disorder Research: Investigated in preclinical models for potential applications in Alzheimer's disease, schizophrenia, and other conditions involving cognitive impairment.
• Chemical Synthesis: Serves as a sophisticated building block for medicinal chemists to create analogs and derivatives with optimized pharmacological profiles.
• Analytical Standard: Employed as a high-purity reference material for method development and quality control in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	Talsaclidine
CAS No.	147025-53-4
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	WAL 2014 FU; (3aR,4S,9bS)-4-(Prop-2-yn-1-yl)-2,3,3a,4,5,9b-hexahydro-1H-benz[e]isoindol-8-ol; 4-Prop-2-ynyl-2,3,3a,4,5,9b-hexahydro-1H-benz[e]isoindol-8-ol; Talsaclidine fumarate (salt); Talsaclidine (WAL 2014)
EINECS	Contact for details

Quality Control

Our Talsaclidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific pharmacopeial or client-defined standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere at 2-8°C to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.