Description

2,5-Difluoro-4-Hydroxybenzoic Acid is a fluorinated aromatic carboxylic acid derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl and a carboxylic acid group on a difluorinated benzene ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to influence molecular polarity and alignment.
• Polymer & Material Science: Acts as a monomer or modifier in the synthesis of specialty polymers, coatings, and advanced materials requiring specific thermal, chemical, or surface properties.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for constructing complex fluorinated aromatic compounds and exploring new chemical reactions.

Basic Information

Product Name	2,5-Difluoro-4-Hydroxybenzoic Acid
CAS No.	146781-23-9
Molecular Formula	C7H4F2O3
Molecular Weight	174.10 g/mol
Synonyms	4-Hydroxy-2,5-difluorobenzoic Acid; 2,5-Difluoro-4-hydroxybenzoic acid; Benzoic acid, 2,5-difluoro-4-hydroxy-; 2,5-Difluoro-4-hydroxy-benzoic acid; 146781-23-9; 4-Hydroxy-2,5-difluorobenzoic acid; 2,5-Difluoro-4-hydroxybenzoic acid (9CI)
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-4-Hydroxybenzoic Acid is produced and tested under a strict quality management system to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.