Description

4-Hydroxy Nonenal Mercapturic Acid is a key mercapturic acid conjugate and a specific biomarker for lipid peroxidation. This compound is of significant value in biochemical research and diagnostic development for assessing oxidative stress and related cellular damage. It is primarily required by researchers and manufacturers in the fields of analytical chemistry, clinical diagnostics, and pharmaceutical development.

Application

• Biomarker for Oxidative Stress: Used in clinical and preclinical studies to quantify lipid peroxidation products as indicators of oxidative damage.
• Reference Standard: Serves as a high-purity analytical standard for the calibration and validation of LC-MS/MS and HPLC methods in bioanalytical laboratories.
• Diagnostic Kit Development: A critical component in the development of immunoassays and other diagnostic tests designed to measure oxidative stress markers.
• Toxicology Research: Employed in studies investigating the mechanisms of toxicity induced by chemicals, drugs, or environmental factors that promote lipid peroxidation.
• Nutritional & Pharmaceutical Research: Used to evaluate the efficacy of antioxidants, nutraceuticals, and therapeutic agents in mitigating oxidative stress.
• Metabolomics Studies: An important metabolite identified in pathways related to fatty acid oxidation and cellular redox status.

Basic Information

Product Name	4-Hydroxy Nonenal Mercapturic Acid
CAS No.	146764-24-1
Molecular Formula	C15H25NO5S
Molecular Weight	331.43 g/mol
Synonyms	4-HNE-MA; 4-Hydroxynonenal Mercapturate; N-Acetyl-S-(4-hydroxynonyl)-L-cysteine; HNE-Mercapturic Acid; 1,4-Dihydroxynonene Mercapturic Acid; Lipid Peroxidation Biomarker; 4-Hydroxy-2-nonenal Mercapturic Acid; L-Cysteine, N-acetyl-S-(4-hydroxynonyl)-
EINECS	Contact for details

Quality Control

Our 4-Hydroxy Nonenal Mercapturic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC and LC-MS/MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider storage under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	< 10 ppm
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.