Description

(S)-1-(Diphenylphosphino)-2-Amino-3-Methylbutane, Min. 97% is a high-purity chiral phosphine ligand, a critical component in asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, crucial for producing single-isomer pharmaceuticals and fine chemicals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-performance ligands for complex synthetic routes.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediates.
• Catalyst component in enantioselective C-C and C-X bond-forming reactions.
• Key reagent for the synthesis of chiral active pharmaceutical ingredients (APIs).
• Use in the development of novel catalytic systems for agrochemical production.
• Research and development of new asymmetric synthetic methodologies in academia and industry.
• Precursor for the synthesis of more complex, tailored phosphine ligands.

Basic Information

Product Name	(S)-1-(Diphenylphosphino)-2-Amino-3-Methylbutane, Min. 97%
CAS No.	146476-37-1
Molecular Formula	C₁₇H₂₂NP
Molecular Weight	271.34 g/mol
Synonyms	(S)-1-(Diphenylphosphino)-2-amino-3-methylbutane; (S)-2-Amino-3-methyl-1-(diphenylphosphino)butane; (S)-Valphos; (S)-2-(Diphenylphosphino)-1-isopropyl-ethylamine; (S)-1-Isopropyl-2-(diphenylphosphino)ethylamine; (S)-P,N-Ligand; Chiral Amino Phosphine Ligand
EINECS	Contact for details

Quality Control

Our (S)-1-(Diphenylphosphino)-2-Amino-3-Methylbutane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical assay, to ensure it meets the specified minimum 97% purity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our rigorous internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	Min. 97.0%
Chiral Purity (HPLC)	Min. 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.