Description

5-Cyano-2-Fluorobenzoic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a nitrile group on a fluorinated benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated benzoic acid scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and electron-transport materials.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: Used as a model substrate in studies of fluorinated aromatic compound reactivity and further functionalization.

Basic Information

Product Name	5-Cyano-2-Fluorobenzoic Acid
CAS No.	146328-87-2
Molecular Formula	C8H4FNO2
Molecular Weight	165.12 g/mol
Synonyms	2-Fluoro-5-cyanobenzoic Acid; 5-Cyano-2-fluorobenzoic Acid; Benzoic acid, 5-cyano-2-fluoro-; 2-Fluor-5-cyanbenzoesäure (German); Acide 5-cyano-2-fluorobenzoïque (French); 146328-87-2; 5-Cyano-2-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 5-Cyano-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.