Description

5-Bromo-2-Fluorobenzoic Acid is a high-purity halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional aromatic structure, which allows for selective chemical modifications at both the bromine and carboxylic acid sites. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents. Its reliable quality and consistent supply are paramount for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig couplings.
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and polymers where fluorinated and brominated aromatics impart desired properties.
• Custom Synthesis and Contract Manufacturing: An important starting material for custom chemical synthesis services catering to the needs of biotechnology and fine chemical companies.

Basic Information

Product Name	5-Bromo-2-Fluorobenzoic Acid
CAS No.	146328-85-0
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	2-Fluoro-5-bromobenzoic acid; 5-Bromo-2-fluorobenzoic acid; Benzoic acid, 5-bromo-2-fluoro-; 5-Bromo-2-fluorobenzenecarboxylic acid; 146328-85-0; 2-Fluoro-5-bromobenzenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and conformity to customer specifications. We provide full traceability and support our products with detailed Certificates of Analysis (COA) upon request, ensuring compliance with the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.