Description

2-Fluoro-5-Phenylbenzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional structure, which allows for selective derivatization at both the carboxylic acid and the fluorinated phenyl ring, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic semiconductors and liquid crystal molecules used in display technologies.
• Polymer Modification: Incorporated as a monomer or additive to impart specific properties like chemical resistance or altered polarity to specialty polymers.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination chemistry and Suzuki-Miyaura cross-coupling reactions.
• Fluorescent Probe Synthesis: Used in the creation of fluorophore tags and molecular probes for biochemical sensing and diagnostic applications.

Basic Information

Product Name	2-Fluoro-5-Phenylbenzoic Acid
CAS No.	146328-84-9
Molecular Formula	C13H9FO2
Molecular Weight	216.21 g/mol
Synonyms	5-Phenyl-2-fluorobenzoic Acid; [1,1'-Biphenyl]-2-carboxylic acid, 2'-fluoro-; 2'-Fluoro[1,1'-biphenyl]-2-carboxylic acid; 2-Fluoro-5-phenylbenzoic acid; 2-Fluoro[1,1'-biphenyl]-2'-carboxylic acid; 2-Fluoro-5-phenyl-benzoic acid; 2-Fluorobiphenyl-2'-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Phenylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.