Description

Methyl2-Fluoro-6-Iodobenzoate CAS NO 146014-66-6 is a high-purity, multi-functional halogenated aromatic ester, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both fluorine and iodine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in cross-coupling reactions (e.g., Suzuki, Sonogashira) and organocatalysts.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers where halogenated aromatics tune optical and electronic properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for imaging and diagnostic applications due to the reactivity of the iodine moiety.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	Methyl 2-Fluoro-6-Iodobenzoate
CAS No.	146014-66-6
Molecular Formula	C8H6FIO2
Molecular Weight	280.04 g/mol
Synonyms	Methyl 2-Fluoro-6-iodobenzoate; 2-Fluoro-6-iodobenzoic Acid Methyl Ester; Benzoic acid, 2-fluoro-6-iodo-, methyl ester; Methyl 2-fluoro-6-iodobenzenecarboxylate; Methyl o-fluoro-o'-iodobenzoate; 146014-66-6; Methyl 2-fluoro-6-iodobenzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Fluoro-6-Iodobenzoate is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.