Description

2,6-Diazabicyclo[3.2.0]Heptane-2-Carboxamide,n-Methyl-7-Oxo-,(1S)-(9Ci) is a high-purity, stereochemically defined bicyclic lactam compound, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in its complex, constrained molecular architecture, which is essential for constructing novel bioactive molecules with targeted pharmacological properties. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in the areas of enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a privileged scaffold for constructing compound libraries in drug discovery programs targeting various diseases.
• Protease Inhibitor Development: Its bicyclic lactam structure is valuable for mimicking peptide bonds and designing potent enzyme inhibitors.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block to induce stereoselectivity in complex organic transformations.
• Chemical Biology Probes: Used in the development of molecular probes to study biological pathways and protein function.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-fidelity chiral intermediates.

Basic Information

Product Name	2,6-Diazabicyclo[3.2.0]Heptane-2-Carboxamide,n-Methyl-7-Oxo-,(1S)-(9Ci)
CAS No.	145574-52-3
Molecular Formula	C7H11N3O2
Molecular Weight	169.18 g/mol
Synonyms	(1S)-N-Methyl-7-oxo-2,6-diazabicyclo[3.2.0]heptane-2-carboxamide; (1S,5R)-N-Methyl-7-oxo-2,6-diazabicyclo[3.2.0]heptane-2-carboxamide; (1S)-N-Methyl-7-oxo-2,6-diazabicyclo[3.2.0]heptane-2-carboxylic acid amide; 2,6-Diazabicyclo[3.2.0]heptane-2-carboxamide, N-methyl-7-oxo-, (1S)-; Bicyclic Lactam Intermediate; (1S,5R)-enantiomer of the bicyclic lactam carboxamide.
EINECS	Contact for details

Quality Control

Our 2,6-Diazabicyclo[3.2.0]Heptane-2-Carboxamide,n-Methyl-7-Oxo-,(1S)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding research and pre-clinical development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.