Description

Leustroducsin A is a biologically active, small-molecule natural product of significant interest in pharmaceutical research and development. This compound matters as a potent and selective inhibitor of specific cellular signaling pathways, making it a valuable tool for studying disease mechanisms and identifying novel therapeutic targets. Researchers and development teams in the biotechnology and pharmaceutical industries need it for high-throughput screening, target validation, and as a lead compound in drug discovery programs.

Application

• Biochemical Research: Used as a selective chemical probe to investigate and modulate specific kinase or phosphatase activity in cell signaling studies.
• Drug Discovery: Serves as a lead compound or a reference standard in high-throughput screening assays for identifying new therapeutic agents.
• Target Validation: Employed in cellular and animal models to validate the role of specific molecular targets in disease pathways, such as cancer or inflammatory disorders.
• Mechanism of Action Studies: Utilized to elucidate the detailed biochemical mechanisms and downstream effects of pathway inhibition.
• Academic Research: A key reagent in university and institutional labs for fundamental research in cell biology, molecular pharmacology, and chemical biology.
• Reference Standard: Provides a high-purity benchmark for analytical method development, quality control of related compounds, and bioactivity calibration.

Basic Information

Product Name	Leustroducsin A
CAS No.	145142-81-0
Molecular Formula	C21H28O7
Molecular Weight	392.45 g/mol
Synonyms	Leustroducsin A; Leustroducsin; (3S,4S,5S,6R,7S,8S,9R,10S,11S,12R,13S,14S,15R)-4,6,8,10,12,14,15-Heptahydroxy-3,5,7,9,11,13-hexamethyl-1-oxacyclopentadecan-2-one; Antibiotic B-5354a; B-5354a; FR-901,228; Depsipeptide antibiotic B-5354a
EINECS	Contact for details

Quality Control

Our Leustroducsin A is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, generated using validated analytical methods including HPLC and NMR. We adhere to relevant industry standards for research-grade biochemicals to support reliable and reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. For long-term storage, consider storage under an inert atmosphere. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.