Description

Repinotan is a high-purity, non-peptide aminotetralin derivative with significant pharmacological research interest. This compound is valued for its role as a potent and selective serotonin 1A (5-HT1A) receptor agonist, making it a critical reference standard and intermediate in advanced pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology, particularly for the investigation of treatments for conditions such as stroke, anxiety, and depression. Our supply of Repinotan CAS NO 144980-29-0 is characterized by stringent quality control to ensure reliability and consistency for sensitive research and development applications.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for analytical method development, validation, and quality control in API manufacturing.
• Neuroscience Research: Used as a selective pharmacological tool to study the function and modulation of the 5-HT1A receptor system in vitro and in vivo.
• Drug Discovery & Development: Acts as a key intermediate or lead compound in the synthesis and optimization of novel central nervous system (CNS) targeting therapeutics.
• Preclinical Studies: Employed in animal models to investigate potential neuroprotective effects, particularly in the context of cerebral ischemia and stroke recovery.
• Biochemical Assays: Utilized in high-throughput screening (HTS) and receptor binding assays to identify and characterize new drug candidates.
• Academic Research: Supports university and institutional research into serotonin receptor pharmacology and related neurological pathways.

Basic Information

Product Name	Repinotan
CAS No.	144980-29-0
Molecular Formula	C20H28N2O3
Molecular Weight	344.45 g/mol
Synonyms	BAY x 3702; BAY-x-3702; Repinotan hydrochloride; UNII-5V2W6K4H1C; (R)-2-[4-[(Chroman-2-ylmethyl)amino]butyl]-1,1-dioxo-1,2-benzothiazol-3-one; 1,2-Benzisothiazol-3(2H)-one, 2-[4-[[(2R)-2H-1-benzopyran-2-ylmethyl]amino]butyl]-, 1,1-dioxide
EINECS	Contact for details

Quality Control

Every batch of Repinotan is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical documentation to support your research and regulatory needs. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation, and impurity profiles. Our quality commitment ensures the material meets the high standards required for pharmaceutical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.