Description

Benzeneacetyl Chloride, 3-Fluoro-α-Hydroxy- (9Ci) is a specialized fluorinated organic building block that serves as a critical intermediate in advanced synthetic chemistry. Its unique structure, featuring both an acid chloride and a hydroxyl group on a fluorinated aromatic ring, enables precise molecular construction for high-value applications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require reliable, high-purity intermediates for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated pesticides and herbicides to enhance efficacy and environmental profile.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized in the creation of fluorinated probes and tags for studying biological mechanisms and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities performing bespoke synthesis for clients.

Basic Information

Product Name	Benzeneacetyl Chloride, 3-Fluoro-α-Hydroxy- (9Ci)
CAS No.	144916-96-1
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	3-Fluoro-α-hydroxybenzeneacetyl chloride; 2-(3-Fluorophenyl)-2-hydroxyacetyl chloride; (3-Fluorophenyl)(hydroxy)acetyl chloride; α-Hydroxy-3-fluorophenylacetyl chloride; 3-Fluoro-mandeloyl chloride; 2-Hydroxy-2-(3-fluorophenyl)acetyl chloride; (RS)-2-(3-Fluorophenyl)-2-hydroxyacetyl chloride
EINECS	Contact for details

Quality Control

Our production of Benzeneacetyl Chloride, 3-Fluoro-α-Hydroxy- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.