Description

Carbovir Monophosphate is a nucleotide analogue monophosphate, a key intermediate in the synthesis of advanced antiviral agents. This compound is of critical importance for pharmaceutical research and development, particularly in the creation of nucleoside reverse transcriptase inhibitors (NRTIs). It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of treatments for viral infections, including HIV. Carbovir Monophosphate CAS NO 144490-73-3 represents a high-purity building block essential for ensuring the efficacy and safety of final drug products.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of carbovir and related antiviral nucleoside analogues.
• Antiviral Drug Research: Used in R&D for developing new nucleoside reverse transcriptase inhibitors (NRTIs) targeting HIV and other retroviruses.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed as a key starting material (KSM) or advanced intermediate in GMP-compliant API production processes.
• Biochemical Research: Utilized in enzymatic studies and as a substrate to investigate nucleotide metabolism and polymerase activity.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	Carbovir Monophosphate
CAS No.	144490-73-3
Molecular Formula	C11H14N5O7P
Molecular Weight	359.23 g/mol
Synonyms	Carbovir 5'-Monophosphate; (-)-Carbovir Monophosphate; (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol 5'-(dihydrogen phosphate); 9-[(1S,4R)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]guanine 5'-Monophosphate; NSC 614846; Carbovir MP; Cyclopropylaminopurine cyclopentenylmethanol monophosphate
EINECS	Contact for details

Quality Control

Our Carbovir Monophosphate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, identification by spectroscopic methods, and control of specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development and commercial projects requiring compliance with ICH Q7 guidelines and current Good Manufacturing Practices (cGMP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider desiccated or nitrogen-purged environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0% (Total related substances ≤3.0%)
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.