Description

Emtricitabine is a potent nucleoside reverse transcriptase inhibitor (NRTI) with the CAS number 144371-00-6. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of antiviral therapies. It is primarily required by pharmaceutical manufacturers and research institutions for the formulation of antiretroviral medications.

Application

• Antiretroviral Drug Manufacturing: A key active ingredient in fixed-dose combination therapies for the treatment of HIV-1 infection.
• Pharmaceutical Research & Development: Used in preclinical and clinical studies for developing new antiviral formulations and delivery systems.
• Generic Drug Production: Serves as a critical component in the manufacture of bioequivalent generic versions of branded antiretroviral drugs.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, and other assay methods.
• Pre-Exposure Prophylaxis (PrEP): A fundamental API in medications used for HIV prevention strategies.
• Biochemical Research: Utilized in virology and molecular biology studies to investigate mechanisms of viral replication and inhibition.

Basic Information

Product Name	Emtricitabine
CAS No.	144371-00-6
Molecular Formula	C8H10FN3O3S
Molecular Weight	247.25 g/mol
Synonyms	FTC; Coviracil; (-)-FTC; 5-Fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine; 2',3'-Dideoxy-5-fluoro-3'-thiacytidine; BW 524W91; Emtriva (Brand Name)
EINECS	Contact for details

Quality Control

Our Emtricitabine is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Each batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to ensure full traceability and regulatory support for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Related Substances (HPLC)	Total impurities: NMT 1.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm
Sulfated Ash	NMT 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.