Description

Fomivirsen is a synthetic antisense oligonucleotide designed for targeted therapeutic intervention. This compound is of significant interest for its specific mechanism of action, which involves binding to complementary mRNA sequences to inhibit viral protein synthesis. It is primarily utilized in advanced pharmaceutical research and development, particularly for antiviral applications. Professionals in biotechnology and pharmaceutical manufacturing seek this high-purity material for critical development and production processes.

Application

• Antiviral Pharmaceutical Research: Investigational agent for the study and development of treatments against specific viral infections.
• Biochemical Research: Used as a tool compound to study antisense mechanisms and gene expression regulation in laboratory settings.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Preclinical Development: A key starting material in the formulation and toxicology studies for novel therapeutic candidates.

Basic Information

Product Name	Fomivirsen
CAS No.	144245-52-3
Molecular Formula	C204H247N63O114P20S20
Molecular Weight	7122.8 g/mol (approximate)
Synonyms	Fomivirsen sodium; ISIS 2922; Vitravene; (P-Thio)(C-G-C-G-C-C-G-C-G-C-G-C-G-T-T-G-C-G); Antisense oligonucleotide complementary to human cytomegalovirus (HCMV) mRNA; 21-mer phosphorothioate oligodeoxynucleotide
EINECS	Contact for details

Quality Control

Our Fomivirsen is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant cGMP guidelines for the production of pharmaceutical intermediates and reference standards to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.