Description

(2R,5R)-1,6-Diphenyl-2,5-Hexanediamine CAS NO 144186-34-5 is a high-purity chiral diamine compound characterized by its specific (R,R) stereochemistry. This compound matters as a critical chiral building block and ligand in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective hydrogenation, alkylation, and other C-C bond-forming reactions.
• Agrochemical Research: Used in the development of chiral active ingredients for herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Polymer Chemistry: Employed as a monomer or chain extender in the synthesis of specialty polyamides and polyurethanes with tailored thermal and mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and for studying structure-activity relationships (SAR).
• Liquid Crystal & Advanced Material Precursor: Used in the synthesis of chiral dopants and components for liquid crystal displays (LCDs) and other functional materials.

Basic Information

Product Name	(2R,5R)-1,6-Diphenyl-2,5-Hexanediamine
CAS No.	144186-34-5
Molecular Formula	C18H24N2
Molecular Weight	268.40 g/mol
Synonyms	(2R,5R)-1,6-Diphenylhexane-2,5-diamine; (R,R)-1,6-Diphenyl-2,5-hexanediamine; (R,R)-DPHDA; (2R,5R)-DPHDA; (R,R)-1,6-Diphenylhexamethylenediamine; (2R,5R)-1,6-Diphenylhexamethylenediamine; (R,R)-Hexanediamine, 1,6-diphenyl-; (2R,5R)-Hexanediamine, 1,6-diphenyl-
EINECS	Contact for details

Quality Control

Our (2R,5R)-1,6-Diphenyl-2,5-Hexanediamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect purity and stability. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.