Description

(R)-Alpha,α-Diphenylmethylprolinol is a high-value, non-natural amino alcohol derivative and a versatile chiral building block. Its significance lies in its role as a highly effective chiral ligand and organocatalyst, enabling the synthesis of enantiomerically pure compounds critical to modern pharmaceutical development. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in asymmetric synthesis.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including additions and reductions.
• As an organocatalyst for enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• In the research and development of Active Pharmaceutical Ingredients (APIs) requiring specific stereochemistry.
• For the synthesis of chiral intermediates used in agrochemicals and specialty chemicals.
• In academic and industrial research focused on developing new asymmetric catalytic methodologies.
• As a resolving agent or chiral auxiliary in stereoselective synthesis.

Basic Information

Product Name	(R)-Alpha,α-Diphenylmethylprolinol
CAS No.	144119-12-0
Molecular Formula	C18H21NO
Molecular Weight	267.37 g/mol
Synonyms	(R)-2-(Diphenylhydroxymethyl)pyrrolidine; (R)-α,α-Diphenyl-2-pyrrolidinemethanol; (R)-Diphenylprolinol; (R)-2-(Diphenylhydroxymethyl)pyrrolidine; (R)-α,α-Diphenylpyrrolidin-2-ylmethanol; (R)-DPP; (R)-Diphenyl(2-pyrrolidinyl)methanol; (R)-Hydroxydiphenylmethylpyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-Alpha,α-Diphenylmethylprolinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for catalytic and synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible performance and lot-to-lot consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.