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(R)-(-)-1,2-Diaminopropane Sulfate CAS NO 144118-44-5
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CAS No.:144118-44-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-(-)-1,2-Diaminopropane Sulfate is a high-purity chiral diamine salt, a critical building block in asymmetric synthesis and pharmaceutical manufacturing. Its value lies in its role as a versatile chiral ligand and resolving agent, enabling the production of enantiomerically pure compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-stereochemical fidelity for advanced intermediates and active ingredients.
Application
- Pharmaceutical Intermediates: A key chiral synthon in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for cardiovascular and central nervous system drugs.
- Asymmetric Catalysis: Serves as a precursor for chiral ligands and catalysts used in asymmetric hydrogenation and other enantioselective transformations.
- Chiral Resolution: Employed as a resolving agent for the separation of racemic mixtures of carboxylic acids and other acidic compounds.
- Agrochemical Synthesis: Used in the development of chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
- Fine Chemical Production: Integral to the manufacture of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.
- Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and chiral compound libraries.
Basic Information
| Product Name | (R)-(-)-1,2-Diaminopropane Sulfate |
| CAS No. | 144118-44-5 |
| Molecular Formula | C₃H₁₀N₂ • H₂SO₄ / C₃H₁₂N₂O₄S |
| Molecular Weight | 184.21 g/mol |
| Synonyms | (R)-1,2-Diaminopropane Hemisulfate; (R)-(-)-1,2-Propanediamine Sulfate; (R)-1,2-Diaminopropane Sulfate Salt; (R)-Propane-1,2-diamine Sulfate; (R)-DAP Sulfate; (2R)-1,2-Diaminopropane Sulfate; (R)-1,2-Diammoniopropane Sulfate; (R)-1,2-PDA Sulfate |
| EINECS | Contact for details |
Quality Control
Our (R)-(-)-1,2-Diaminopropane Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Chiral Purity (HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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