Description

2-Amino-5-Bromo-4-Fluorobenzoicacid (CAS NO 143945-65-7) is a high-value halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring amino, bromo, and fluoro substituents, makes it an essential intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed cross-coupling reactions, crucial for constructing complex carbon-heteroatom bonds.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Amino-5-Bromo-4-Fluorobenzoicacid
CAS No.	143945-65-7
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	5-Bromo-4-fluoro-2-aminobenzoic acid; 2-Amino-5-bromo-4-fluorobenzoic acid; 4-Fluoro-2-amino-5-bromobenzoic acid; Benzoic acid, 2-amino-5-bromo-4-fluoro-; 5-Bromo-4-fluoroanthranilic acid; 143945-65-7; 2-Amino-5-bromo-4-fluorobenzoic acid (ACI); 4-Fluoro-5-bromoanthranilic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-4-Fluorobenzoicacid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance documentation for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.