Description

D-Glucosamine-1-13C Hydrochloride is a stable isotope-labeled derivative of glucosamine, where the carbon-1 position is enriched with the non-radioactive 13C isotope. This compound is essential for advanced research and analytical applications requiring precise metabolic tracing and quantification. It is primarily utilized by scientists and manufacturers in the pharmaceutical, nutraceutical, and life science research sectors for applications such as metabolic pathway studies, drug development, and the production of high-purity internal standards.

Application

• Isotopic Tracer in Metabolic Research: Used to study the metabolic pathways and pharmacokinetics of glucosamine in biological systems.
• Internal Standard for Mass Spectrometry: Serves as a critical reference standard in LC-MS and GC-MS analysis for accurate quantification of glucosamine in complex matrices.
• Pharmaceutical R&D: Employed in the development and testing of novel osteoarthritis treatments and chondroprotective agents.
• Nutraceutical Analysis: Used to verify the purity, authenticity, and dosage of glucosamine in dietary supplement formulations.
• Biochemical Synthesis: Acts as a labeled precursor for the synthesis of more complex 13C-labeled glycoproteins, glycosaminoglycans, and other biomolecules.
• Clinical Research: Facilitates human and animal studies investigating joint health, cartilage metabolism, and the efficacy of therapeutic interventions.

Basic Information

Product Name	D-Glucosamine-1-13C Hydrochloride
CAS No.	143553-09-7
Molecular Formula	C613CH14NO5•HCl
Molecular Weight	216.61 g/mol (for 13C1 isotopologue)
Synonyms	(2R,3R,4R,5S)-3-Amino-6-(hydroxymethyl)-5-13C-tetrahydro-2H-pyran-2,4-diol hydrochloride; 2-Amino-2-deoxy-13C1-D-glucose hydrochloride; Chitosamine-1-13C hydrochloride; D-Glucosamine-1-13C HCl; GlcN-1-13C•HCl; 1-13C-Glucosamine hydrochloride; D-(+)-Glucosamine-1-13C hydrochloride
EINECS	Contact for details

Quality Control

Our D-Glucosamine-1-13C Hydrochloride is manufactured under strict quality control protocols to ensure high isotopic and chemical purity, essential for sensitive research applications. Each batch is analyzed to confirm identity, isotopic enrichment, and purity, with comprehensive testing including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic purity, and impurities are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (13C)	≥ 99 atom % 13C
Chemical Purity	≥ 98.0%
Specific Rotation	+70.0° to +73.0° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.