Description

2,3,5,6-Tetrafluoro-4-Hydroxybenzoic Acid Hydrate is a fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a hydroxy group and four fluorine atoms on the benzoic acid core, makes it a versatile intermediate for introducing specific steric and electronic properties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for creating advanced herbicides, pesticides, and plant growth regulators with enhanced activity and selectivity.
• Liquid Crystal Materials: Used in the production of fluorinated components for high-performance liquid crystal displays (LCDs).
• Polymer Modification: Intermediate for synthesizing specialty monomers that impart chemical resistance and stability to advanced polymers.
• Organic Synthesis Reagent: Versatile reagent for introducing the tetrafluoro-hydroxybenzoate moiety into complex organic frameworks in research and development.
• Coordination Chemistry: Ligand for metal complexes used in catalysis and material science applications.

Basic Information

Product Name	2,3,5,6-Tetrafluoro-4-Hydroxybenzoic Acid Hydrate
CAS No.	143201-17-6
Molecular Formula	C7H2F4O3 · xH2O
Molecular Weight	214.08 (Anhydrous basis)
Synonyms	4-Hydroxy-2,3,5,6-tetrafluorobenzoic Acid Hydrate; 2,3,5,6-Tetrafluoro-4-hydroxybenzoic Acid Monohydrate; Benzoic acid, 2,3,5,6-tetrafluoro-4-hydroxy-, hydrate; TFBH; Tetrafluorohydroxybenzoic Acid Hydrate; 143201-17-6 (Hydrate); 2,3,5,6-Tetrafluoro-4-hydroxybenzoic acid water adduct
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrafluoro-4-Hydroxybenzoic Acid Hydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results for parameters including assay, water content, and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates under GMP or research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The hydrate form may be hygroscopic; protect from excessive moisture to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	As per hydrate stoichiometry
Related Substances (HPLC)	Total impurities ≤2.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.