Description

2-Methylthio-4-Trifluoromethylbenzoic Acid is a high-value fluorinated aromatic building block characterized by its trifluoromethyl and methylthio substituents. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for enhanced bioactivity and pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group is a common bioisostere.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and advanced organic electronic materials due to its unique electronic properties.
• Chemical Biology & Proteomics: Employed as a building block for designing chemical probes and affinity tags to study biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up services for clients in life sciences.

Basic Information

Product Name	2-Methylthio-4-Trifluoromethylbenzoic Acid
CAS No.	142994-05-6
Molecular Formula	C9H7F3O2S
Molecular Weight	236.21 g/mol
Synonyms	4-(Trifluoromethyl)-2-(methylthio)benzoic Acid; 2-(Methylthio)-4-(trifluoromethyl)benzoic Acid; Benzoic acid, 2-(methylthio)-4-(trifluoromethyl)-; α,α,α-Trifluoro-2-methylmercapto-p-toluic Acid; 2-Methylmercapto-4-trifluoromethylbenzoic Acid; 2-Methylsulfanyl-4-trifluoromethylbenzoic Acid; 2-(Methylsulfanyl)-4-(trifluoromethyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Methylthio-4-Trifluoromethylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.