Description

Acyclovir L-Isoleucinate is a high-purity pharmaceutical salt formed from the antiviral agent acyclovir and the essential amino acid L-isoleucine. This compound is specifically engineered to enhance the physicochemical properties and bioavailability of the parent drug, making it a critical intermediate in advanced pharmaceutical manufacturing. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development and production of next-generation antiviral formulations and prodrugs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel antiviral prodrugs and improved drug formulations.
• Antiviral Drug Development: Used in R&D for creating enhanced versions of acyclovir with potentially better solubility, stability, or targeted delivery.
• Bioconjugation Studies: Employed in research exploring amino acid-drug conjugates to modulate pharmacokinetic profiles.
• Reference Standard: Functions as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical labs.
• Preclinical Research: Utilized in animal studies to evaluate the efficacy and safety of new antiviral candidates derived from acyclovir.

Basic Information

Product Name	Acyclovir L-Isoleucinate
CAS No.	142963-63-1
Molecular Formula	C18H28N6O5
Molecular Weight	408.45 g/mol
Synonyms	2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl (2S,3S)-2-Amino-3-methylpentanoate; Acyclovir L-Isoleucine Ester; Acyclovir Isobutylacetate Ester; L-Isoleucine Acyclovir Ester; Acyclovir Ester with L-Isoleucine; Acyclovir-Ile; ACV-Ile; Antiviral Prodrug Intermediate
EINECS	Contact for details

Quality Control

Our Acyclovir L-Isoleucinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identification via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.