Description

Valaciclovir is the L-valyl ester prodrug of the antiviral agent acyclovir, designed to enhance oral bioavailability. This compound is a critical active pharmaceutical ingredient (API) in the global fight against herpesvirus infections. It is primarily utilized by pharmaceutical manufacturers for the formulation of antiviral medications targeting conditions such as herpes zoster (shingles), genital herpes, and herpes labialis (cold sores).

Application

• Antiviral Pharmaceutical Formulations: Primary API in oral tablets and capsules for systemic antiviral therapy.
• Treatment of Herpes Zoster: Used in medications to reduce the severity and duration of shingles outbreaks.
• Management of Genital Herpes: Key component in therapies for initial episodes and suppressive treatment of recurrent genital herpes.
• Cold Sore Treatment: Incorporated into formulations for the treatment of herpes labialis.
• Research & Development: Serves as a reference standard and starting material in antiviral drug discovery and pharmacokinetic studies.
• Contract Manufacturing: Supplied to CDMOs for the production of generic and branded antiviral drugs under cGMP guidelines.

Basic Information

Product Name	Valaciclovir
CAS No.	142963-60-8
Molecular Formula	C13H20N6O4
Molecular Weight	324.34 g/mol
Synonyms	Valacyclovir; L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester; Valtrex (Brand Name); Zelitrex (Brand Name); BW256U87; 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate; Acyclovir L-valyl ester
EINECS	Contact for details

Quality Control

Our Valaciclovir is manufactured and tested to meet stringent pharmacopeial standards, including USP and EP monographs. Every batch undergoes comprehensive analytical testing for identity, purity, and potency. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Related Substances (HPLC)	Total impurities: NMT 1.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm
Microbial Enumeration	Complies with EP/USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.