Description

(+)(-)-8,12-trans-9-Oxo-Prosta-5,14-Dienoic Acid CAS NO 142666-04-4 is a high-purity synthetic prostaglandin derivative, a key intermediate in advanced pharmaceutical research and development. This compound matters for its critical role in the synthesis of prostaglandin analogs, which are pivotal in studying and developing therapeutics for a range of physiological processes. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on cardiovascular, ocular, and inflammatory research.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel prostaglandin-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe compound in studies of prostaglandin receptors, signal transduction pathways, and enzyme interactions.
• Ophthalmic Drug Development: Serves as a precursor in the research and production of prostaglandin analogs used to treat glaucoma and ocular hypertension.
• Cardiovascular Research: Employed in preclinical studies investigating the role of prostaglandins in vascular tone, platelet aggregation, and inflammation.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	(+)(-)-8,12-trans-9-Oxo-Prosta-5,14-Dienoic Acid
CAS No.	142666-04-4
Molecular Formula	C₂₀H₃₀O₄
Molecular Weight	334.45 g/mol
Synonyms	9-Oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid; 9-Keto-11α,15S-dihydroxy-prosta-5,13-dienoic acid; Prostaglandin E1 δ5,6-dehydrogenation metabolite; 9-Oxo-PGE1; 9-Keto-PGE1; 11α,15S-Dihydroxy-9-oxoprosta-5,13-dienoic acid; U-46619 metabolite
EINECS	Contact for details

Quality Control

Our (+)(-)-8,12-trans-9-Oxo-Prosta-5,14-Dienoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, impurities, and analytical results are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.