Description

(-)-N,n-Dimethyl-1-(3-Methoxyphenyl)-2-Pyrrolidinemethanamine Fumarate is a high-purity, single-enantiomer organic salt with significant relevance in advanced chemical synthesis. This compound matters as a critical chiral intermediate or reference standard for research and development in regulated industries, where precise stereochemistry and consistent quality are paramount. It is needed by pharmaceutical R&D teams, analytical laboratories, and fine chemical manufacturers developing novel therapeutic agents or high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Analytical Reference Standard: Used as a high-purity standard in HPLC, GC, or LC-MS methods for method development, validation, and quality control testing.
• Chemical Research & Development: Employed in academic and industrial R&D for studying structure-activity relationships (SAR), enantioselective catalysis, and novel synthetic pathways.
• Process Chemistry: Acts as a starting material or intermediate in scale-up and process optimization for the manufacture of complex organic molecules.
• Metabolite Synthesis: Utilized in the preparation of drug metabolites for pharmacological and toxicological studies.

Basic Information

Product Name	(-)-N,n-Dimethyl-1-(3-Methoxyphenyl)-2-Pyrrolidinemethanamine Fumarate
CAS No.	142470-01-7
Molecular Formula	C16H24N2O • C4H4O4
Molecular Weight	376.43 g/mol
Synonyms	(-)-N,N-Dimethyl-1-(3-methoxyphenyl)-2-pyrrolidinemethanamine fumarate; (2R)-1-(3-Methoxyphenyl)-N,N-dimethyl-2-pyrrolidinemethanamine (E)-2-butenedioate (1:1); (R)-N,N-Dimethyl-1-(3-methoxyphenyl)-2-pyrrolidinemethanamine fumarate; Fumaric acid, compd. with (R)-N,N-dimethyl-1-(3-methoxyphenyl)-2-pyrrolidinemethanamine (1:1); (R)-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)pyrrolidine fumarate
EINECS	Contact for details

Quality Control

Our (-)-N,n-Dimethyl-1-(3-Methoxyphenyl)-2-Pyrrolidinemethanamine Fumarate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing specific results for assay, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.