Description

(-)-1-(3-(1-Methylethyl)Phenyl)-2-Pyrrolidinemethanamine Fumarate is a high-purity chiral amine fumarate salt, a critical intermediate in advanced pharmaceutical synthesis. Its primary value lies in its role as a key building block for the development of active pharmaceutical ingredients (APIs) with specific stereochemical requirements. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel therapeutic agents or high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new central nervous system (CNS) active drugs and other therapeutic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key precursor in multi-step synthetic routes for producing target APIs with defined stereochemistry.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides where specific biological activity is required.
• Asymmetric Catalysis Ligand Precursor: Potential use in the synthesis of chiral ligands for asymmetric synthesis and catalysis.
• Fine Chemical Manufacturing: Employed in the production of complex, high-value specialty chemicals for various industrial applications.
• Academic & Contract Research: A valuable compound for medicinal chemistry research, process development, and scale-up studies in academic and CRO/CMO settings.

Basic Information

Product Name	(-)-1-(3-(1-Methylethyl)Phenyl)-2-Pyrrolidinemethanamine Fumarate
CAS No.	142469-93-0
Molecular Formula	C16H24N2 • C4H4O4
Molecular Weight	376.45 g/mol
Synonyms	(-)-1-(3-Isopropylphenyl)-2-(pyrrolidin-1-yl)ethanamine Fumarate; (R)-1-(3-Isopropylphenyl)-2-(pyrrolidin-1-yl)ethanamine Fumarate; 1-(3-Isopropylphenyl)-2-(1-pyrrolidinyl)ethylamine Fumarate (1:1); 1-(3-Isopropylphenyl)-2-pyrrolidin-1-ylethanamine Fumarate; Fumaric acid, compd. with 1-[3-(1-methylethyl)phenyl]-2-(1-pyrrolidinyl)ethanamine (1:1); (R)-1-(3-Isopropylphenyl)-2-(pyrrolidin-1-yl)ethan-1-amine Fumarate
EINECS	Contact for details

Quality Control

Our (-)-1-(3-(1-Methylethyl)Phenyl)-2-Pyrrolidinemethanamine Fumarate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing chiral purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.